Endocrine Abstracts

Type 2 diabetes mellitus (T2DM) has historically been considered an exclusive disease of adulthood until late 1970’s when reports of increased prevalence in pediatric age group emerged in the literature. The concerning increase in the rate of diagnosis of T2DM in children and adolescents has continued parallel to the increasing rates of obesity. The disease is not specific to the United States, it has been recognized as a global problem.T2DM of yout...

Aim: We had the aim to determine the insulin treatment strategy that could prevent or decrease the occurrence of hypoglycaemia while providing better regulation of blood glucose in Tip 2 diabetic patients with cardiac failure.Method: The patients demonstrating similar characteristics with respect to the age, body mass index, the duration of diabetes and heart failure were randomized into two groups as insulin glargine (n: 19) and NPH (n: 11...

Glycogen storage disease (GSD) type 1 is an autosomal recessive disorder in which there is problem in glucose 6 phosphatase system. Glucose-6-phosphate transport protein deficiency is found in GSD type 1b. There is disorder in glucose metabolism, lack of glucose production in liver. Hypoglycemia, seizures, lactic acidosis, hyperuricemia and hyperlipidemia are some of the components. Affected people may also have short stature, pancytopenia and inflammatory bowel disease. Our a...

Introduction: Radioiodine ablation with a whole-body scan is a well known therapeutic regimen for differentiated thyroid cancer. I-131 uptake in the breast has been described with a variety of normal and pathologic conditions such as gynecomastia, supernumerary breasts, fibroadenoma and lactational duct cyst or galactocele. Here we report a case with an incidental radioiodine uptake in breast who turned out to be breast cancer.Case report: A 70 years old...

Summary: Hyperuricemia is associated with glucose metabolism disorders clinically. In this study, we evaluated the relationship between serum uric acid concentrations and some insulin resistance/sensitivity parameters in Turkish type 2 diabetes mellitus patients.Methods: The anthropometric and laboratory data of 87 type 2 diabetes patients of both sexes (35 male, 52 female) were evaluated retrospectively. HOMA-IR (homeostatic model of insulin resistance)...

Introduction: Left ventricular diastolic dysfunction (LVDD) is a common cause of heart failure in obese patients. The aim of this study is to evaluate diastolic function and its relation to body mass index (BMI) in overweight and obese patients by using transthoracic echocardiography.Material and method: A total of 133 cases were enrolled in the study. All anthropometric and laboratory measures were recorded. After measuring two-dimensional and M-mode ec...

Introduction: Orthorexia (nervosa) is an eating disorder, characterised by an obsession with avoiding foods perceived to be unhealthy. Though it has not been recognised as a pathological entity in Diagnostic and Statistical Manual of Mental Disorders – IV yet, interest in the condition has increased recently. This study aimed to determine the prevalence and risk factors of orthorexia in a group of diabetic patients.Methods and design: 134 (63 female...

Papillary thyroid cancer (PTC) is the most frequent thyroid tumour. Medullary thyroid cancer (MTC) however, is very rare. We report a case of coexistent medullary and papillary carcinomas in two different foci in a patient with family history of TPC in a first-degree relative.Case: A 65-year-old female was examined for multinodular goiter (MNG). She had a family history of thyroid papillary carcinoma in her elder sister. Free T4, free T3<...

Background: Osteoporosis is a common problem in postmenoausal women. There is limited data about the physiological importance of endogenous testosterone on bone mineral density (BMD) in older women is poorly understood.Aim: The aim of this study was to evaluate association of endogeneous testosterone with BMD and BMI.Materials-methods: This cross-sectional study included 64 patients (45–85 year) postmenopausal women; their dem...

Proton pump inhibitor (PPI) drugs which are used safely to treat peptic ulcus disease since 2 decades, moderately increases gastrin hormone by decreasing gastric acid secretion. Preclinical studies show that gastrin itself, or drugs that increase gastrin levels such as PPIs, increase islet cell mass and improve glycaemic control. To the best of our knowledge one prospective and some retrospective studies claim that PPI medication in diabetic patients leads to an average decrea...